Монголын Анагаахын Сэтгүүлүүдийн Холбоо (МАСХ)
Mongolian Journal of Health Sciences, 2011, 1(8)
Effect of horse and goat meat on acute pulmonary edema induced by adrenalin hydrochloride in mice
( Судалгааны өгүүлэл )

Alimaa Tugjamba, MD, M.Sc1

Molor-Erdene Perenlei, MD, PhD1

Prof.Tumurbaatar Namral, MD, Ph.D1

Acc.Prof.Chimedragchaa Chimedtseren, MD, Ph.D2

1School of Traditional Medicine, Health Sciences University of Mongolia

2Traditional Medical ScienceTechnology and Production Corporation of Mongolia

 
Абстракт

Diet is one of four  treatment  methods of Traditional Mongolian Medicine  (TMM) and  it  plays an  important  role  in  prevention and treatment of  diseases.  Traditional principles of disease treatment and prevention with diet can be combined with conventional medical practices and may lead to a possibility of developing new treatment and preventive strategies.  In this  study, the  effect  of  horse  meat  which  has  a  hot  quality  and  goat  meat  which  has a  cold  quality were examined on acute  pulmonary  edema  induced  by adrenalin  hydrochloride in  mice in the spring and autumn. Mice were given 2.85 g/kg of horse or goat meat for 14 days in the spring and autumn. Then acute pulmonary edema was induced in mice by injecting adrenaline hydrochloride at a concentration of 25 mg/kg. Euphillin (2.1 mg/kg) was used as a standard medicine for comparison.  After administration of adrenalin hydrochloride, mice  were  sacrificed  and  lung tissues  were  removed  for  measurements  of  pulmonary surfactant stability coefficient,  pulmonary index,  and alveolar diameter. Histological analysis of the lung tissues were also performed.

Horse meat increased pulmonary surfactant stability coefficient and alveolar diameter in mice given adrenalin hydrochloride in both seasons. Horse meat  had  no significant effects  on pulmonary index  in the  autumn, though  it  reduced  it  in the  spring. Furthermore, histological analysis revealed that horse meat reduced pulmonary edema and improved the repair of alveolar structure in both seasons.  However, goat meat had no effect on pulmonary surfactant stability coefficient and alveolar diameter in mice administered adrenalin hydrochloride in the autumn however, it increased in the spring.  When compared to goat meat, horse meat decreases alveolar collapse and pulmonary edema in mice model of pulmonary edema induced by adrenalin hydrochloride.

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