ЭХЭМҮТ
Objective: To determine clinical and laboratory feature of Ig A nephropathy in children
Material and Method: There were included to this crass sectional and case-control study 112 patients, who were treated in the Cardiovascular and Nephrology department of MCHRC during 2005-2008.
Results: Patients with Henoch-Shonlein nephritis had skin purpura and complained on anorexia 84.0% and sick 56.5%. But the most of patients (79.1%) with IgA nephropathy had no complaints. The disease starts with macrohematuria. 4.3% (n=3) of patients with Henoch-Shonlein nephritis had arterial hypertension and edema together and 2.8% (n=2) of patients with Henoch-Shonlein nephritis had only edema, 1.4% (n=1) of patients with Henoch-Shonlein nephritis had only arterial hypertension. 6.9% (n=3) of patients with Ig A nephropathy nephritis had arterial hypertension and edema, 2.3% (n=1) of patients with Ig A nephropathy nephritis had only edema, 9.3% (n=4) of patients with Ig A nephropathy nephritis had only arterial hypertension. Kidney biopsy was done in 7 cases. 5 children from them were diagnosed with Ig A nephropathy. But serum level of Ig A was elevated in 2 patients.
Conclusion: There was nonclinical difference in Henoch-Shonlein nephritis and in Ig A nephropathy. Except purpura in children with Henoch-Shonlein nephritis and low serum protein in children with Ig A nephropathy. Some cases of Ig A nephropathy were revealed by urine syndromes. Kidney biopsy showed both cases had glomerular Ig A deposits, but glomerular changes were different.
