ЭХЭМҮТ
Background: Pediatric acute lung injury and acute respiratory distress syndrome is a devastat- ing lung condition with high mortality being the end result of a wide variety of inciting events. The main purposes of the study were to determine incidence of the conditions and to report outcome of children.
Materials and methods: The case records of children admitted to the National Centre for Maternal and Child Health due to acute lung injury and acute respiratory distress syndrome from 2007 to 2012 were retrospectively and prospectively reviewed. The International criteria were used to diagnose the cases: (a) acute onset, (b) bilateral infiltrates on chest radiography, (c) arterial oxygen tension/frac- tion of O2 in the inspired gases, i.e., PaO2/FiO2 ratio less than 300 for acute lung injury and less that 200 for acute respiratory distress syndrome, and (d) absence of clinical evidence of left atrial hyperten- sion. Statistical analysis was done using descriptive and logistic regression analysis using Stata 10 software.
Results: A total of 61 children were diagnosed as acute lung injury and acute respiratory distress syndrome during study period giving an incidence of 11.5/1000 admissions. The most (57.4%) cases were males. Out of the total cases 44.3% (27 cases) was diagnosed with acute lung injury and 55.7% (34 cases) was diagnosed with acute respiratory distress syndrome. Primary lung pathology contrib- uted to a (59.02%) cases while the rest had nonpulmonary causes. The hospital mortality rate was 60.0%.
Conclusion: The high incidence and mortality of pediatric acute lung injury and acute respira- tory distress syndrome may necessitate more efforts to improve the accurate diagnosis and treatment system in the country.
