Монголын Анагаахын Сэтгүүлүүдийн Холбоо (МАСХ)
Монголын анагаах ухаан, 2010, 2(152)
Монголын ахимаг насны эрчүүдийн цусны ийлэдсний адипонектинийг түвшинг тодорхойлсон дүн
( Судалгааны өгүүлэл )

С.Болор-Эрдэнэ, Ж.Мөнхцэцэг

 
Абстракт

Introduction: 

Adipose tissue exclusively secretes adiponectin, a 244–amino-acid protein that regulates the metabolism of lipids and glucose and circulates quite abundantly in plasma. Adiponectin were still strongly associated with an increased diabetes risk in men; but the association for women was no longer statistically significant. Adiponectin decreases insulin resistance and body weight by increasing lipid oxidation in muscle and other organs such as the pancreas and liver.
Goal: 
To define of adiponectin level in aging man living in Ulaanbaatar city. Material and Methods: Randomly selected 84 men aged 35-90 years old were involved to this study. Vein blood were collected, the serum were separated and were frozen until assayed by immunosorbent assay. Morning baseline adiponectin were determined in the sera. We used ELISA kit from Mesdia company (Korea).
Result and Discussion: 
Average age of all participants was 56.82±12.55 years and was divided in three age groups: 35-60 (31.1%), 61-74 (10%), 74-90 (5.55%). Levels of adiponectin were inversely associated with BMI (r=-0.103), WC (r=-0.173), and TG (r=0.143) and directly associated with age and HDL-C (r=0.117, p 0.001). All people were divided by NCEP criteria in two groups: metabolic syndrome group and healthy control group. Average adiponectin level in metabolic syndrome group was 4.83±7.10 ug/ml, in healthy group it was 5.71±7.53 ug/ml, which shows that adiponectin level is significantly lower in people with metabolic syndrome.
Conclusion:
Adiponectin level was lower in people with metabolic syndrome and it has inverse correlation with waist circumference.
 


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