Инноваци - Шинэ Санаа, Шинэ Нээлт, 2013, 1(7-1)
Relationship between thyroid gland function and serum lipid level in elderly people
( Судалгааны өгүүлэл )
1-Department of Physiology and Pathophysiology’s master student; 2-Health Sciences University of Mongolia, Department of Physiology and Pathophysiology; 3-Health Sciences University of Mongolia, Department of Chemistry and Laboratory; 4-Health Technology College of Mongolia, research and educational center
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Абстракт
PURPOSE
Determine the pituitary thyroid gland axis function abnormalities and relate it with serum lipid level.
MATERIALS AND METHODS
We enrolled 313 elderly people from UB and Orkhon aimag. Serum total TSH, T3, T4 hormones, low –density lipoprotein, high-density lipoprotein, total cholesterol and triglyceride level were defined by ELISA and fully automatic analyzer. All analyses were conducted with the use of SPSS 19.0, MS Excel 2007 program in which mean variables, One way Anova test and bivariate correlations are included.
RESULTS
A total of 313 elder subjects, male 29.4%, female 70.6% and mean age was 71.8±9.8. Pituitary thyroid hormone abnormalities were detected mostly in females (p=0.027), thyroid hormone decrease was noticed in 70-79 age. In all groups serum triglyceride level as in normal range but it was significantly high (p=0.027) in hypothyroid group. Triglyceride level was negatively correlated with total T4 (p<0.01), positively correlated with T3 (p<0.01).
CONCLUSION
Thyroid hormone decrease increases serum lipid especially triglyceride level. Furthermore it increases atherosclerosis risk factor to elderly people thus affects the quality of life.
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