Монголын Анагаахын Сэтгүүлүүдийн Холбоо (МАСХ)
Mongolian Journal of Health Sciences, 2013, 1(10)
Some Cytocine Levels and Microstructure of Brown Adipose Tissue in Marmot and Mouse
( Судалгааны өгүүлэл )

Nyamdorj D1*, Dagdanbazar B1, Uurtuya Sh1, Amgalanbaatar D1, Enebish S1, Munkhtulga L2

1School of Bio-Medicine, HSUM

2School of Health Technology of Mongolia, HSUM

 
Абстракт

Function of brown adipose tissue (BAT) is maintenance to thermogenesis in hibernators and immunity depression in deep hypothermia are suggested there may be have relation between BAT and immunity. However, according to some researchers’ demonstration, BAT is assist to function of immune activity, but immune cells in BAT is not clear so far.  Methods of general and selective histology were used in preparation of microstructure slides of BAT in marmot. BAT CD4+ and CD8+ were counted by Fluorescence-activated cell sorting (FACS) method. Microstructure of BAT in the marmot is showed rich network of blood vessels in lobules of connective tissue, lymphoid tissue accumulation of follicle and blood cells detected in vessels. In this study selected BALB/c model 80-90 day-old healthy male mouse. In the BAT detected total of 31095/μL lymphocytes, as total of lymphocytes CD4+ T cells were 3742/μL (5.20%) and CD8+ T cells were 1868/μL (4.99%), respectively. There have different value of T cell in the peripheral vessel blood and in the BAT is suggested BAT is assist to developing blood cell. 

Ном зүй

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