1School of Biomedicine, Health Sciences University of Mongolia
2 School of Medicine, Health Sciences University of Mongolia
Өгүүллийн PDF-ийг татах
Quantization of circulating hepatitis delta virus RNA is important for determining and monitoring the response to antiviral therapy and for understanding the complex dynamic interactions between hepatitis B virus and hepatitis D virus replication. There are scores of Polymerase Chain Reaction Assay studies on the quantitative molecular level of the hepatitis D Virus. The aim of this study was to evaluate via molecular detection the hepatitis D virus as a co-infection with hepatitis B virus in HBsAg carriers.
The study subjects consisted of 61 patients from the capital city of Mongolia who were infected with the hepatitis B virus. All of the 61 subjects were evaluated for the presence of HBsAg, anti-HBs, HBeAg, anti-HBe, anti-HBc, anti-HDV, anti-HCV, and the presence of HBV-DNA and HDV-RNA.
This study shows that 31.25% of HBsAg carriers had anti-HDV, and hepatitis B and D viruses with a viral load detected at a ratio of 2:4 in the study participants.
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