1Outpatient clinic, Second General Hospital
2Department of Epidemiology and Biostatistics, HSUM
3School of Medicine, HSUM
4Department of Nephrology, HSUM
During the recent years the complications of diabetic nephropathy have become the leading cause of kidney failure and initiate renal disorders are located in the 2nd and 3rd places in America and some counties of Asia and Europe. Diabetic nephropathy has been increasing dramatically that accounts high proportion of deaths. Objective of this study was to study diabetic nephropathy among Type 2 DM patients in Ulaanbaatar. The prevalence of nephropathy of Type 2 DM was studied by hospital based cross sectional method. The sample size was calculated by a formula, estimating prevalence 40%, error 0.25%, and 95% confidence interval. Health questionnaire, physical examination and blood and urine test analyses were done. The study was performed in the 2nd general hospital between June 2010 and April 2011. In the study 123 (58.6%) males aged between 35 and 89, 87 females (41.4%) were participated. The mean age was 60.3 ±10,8. From total number of patients 69.4% were at 55 and older age. It was determined that 14.8% among 210 patients involved in the study had nephropathy. The nephropathy prevalence was increased by age and was the highest among elder patients. Proteinuria level of diabetic nephropathy was: less than 0.5g/L in 6.1%, 0.5-1.0g/L in 3.3%, 1.1-2.9% in 3.8%, more than 3.0g/L in 1.4. In conclusion, prevalence of diabetic nephropathy among patients with type 2 diabetes was 14.8%. In comparison with females the nephropathy prevalence was higher in males. Distribution of diabetic nephropathy has a tendency to increase with the increase of age and period of illness among patients.
2.Brenner Rectors. The Kidney: 2008; 1265-1289
3.Health Development Center, Government of Mongolia. Health Indicators 2007, Ulaanbaatar, 2007.
4. Reports diabetes world health organization. World health organization.2005;Geneva.
5.Baigalmaa. Altaisaikhan Kh. Gelegjamts Kh. S. Kidney microangiopathy in diabetes mellitus.International Society of Nephrology Comgan Continuing Medical Education Meeting- II, 2010, Ulaanbaatar, Mongolia.
6.Tsetsgee D. Bodytsetseg Ts. Yanjmaa S. Byambatseren J. Study on mortality and current situation of diabetes complications.Mongolian medical sciences.2011;1:50-52.
6.Loek T J Pijls., Hendrik de Vries., Didi M. W. Kriegsman., Ab J.M.Donker. Jacquis ThM van Eijk. Determinants of albuminuria in people with Type 2 Diabetes mellitus. Diabetes Res Clin Pract.2011;52:132-143
7.Ching-Heng Lin. Wu-Chang Yang. Shih-Tzer Tsai. Tao-Hsin Tung. Pesus Chou.A community-based study of chronic kidney disease among type 2 diabetes in Kinmen, Taiwan. Diabetes Res Clin Pract. 2007;75;306-312.
8.Kim Y I., Kim C-H., Choi C S., Chung Y E., Lee M S., Lee S I., Park J Y., Hong S K., Lee K.-U. Microalbuminuria is associated with insulin resistance Syndrome independent of hypertension and type 2 diabetes in Korean Population. Diabetes Res Clin Pract.2001;52;145-152.
9. Gall MA, Rossing P, Skott P, et al., Prevalence of micro- and macroalbuminuria, arteria hypertension, retinopathy and large vessel disease in European Type 2 diabetic patients. Diabetologia. 1991;34:655-661.
10. Sasaki A, Horiuchi N, Hasagavawa K, Uehara M. Persistent albuminuria as an index of diabetic nephropathy in type 2 diabetic patients in Osaka, Japan incidence, risk factors, prognosis and causes of death. Diabetes Res Clin Pract. 7 (1989) 299-306.
11. Parving HH, Gai MA., Skott P, et al. Prevalence and causes of Albuminuria in non-insulin-dependent diabetic patients, Kidney Int. 41 (1992) 758-762.
12.Gall MA, Hougaard P, Borch-Johnsen K, Parving HH. Risk factors for development of incipient and overt diabetic nephropathy in patients with non-insulin dependent diabetes mellitus. Br Med J.1997;314:783-788.
13.Salman RA, Basri HA, Sayyad AS, Hearnshaw HM. Prevalence and risk factors of albuminuria in Type 2 diabetes in Bahrain. J Endocrinol Invest.2009; 32(9):746-751.
14. Maslova OV, Suntsov Y, Shestakova MV, Kazakova IV, Vikulova OK, Sukhareva OY, Martynov SA. Prevalence of diabetic nephropathy and chronic kidney diseases in diabetes mellitus in Russian Federation. Clinical Nephrology. 2010:3:45-50.
15.Nelson R G. Hanson R L. Knowler P N. Bennett P N. Pettitt D J. Incidence and determinants of elevated urinary albumin excretion in Pima Indians with NIDDM. Diabetes care 1995;18:182-187.
16.Klein R. Klein B E K. Moss S E. Incidence of gross proteinuria in older- onset diabetes. Diabetes.1993;16: 381-389.
17.Ballard D J. Humphrey L L. Melton J et al Epidiomolgy of persistent proteinuria in type 2 diabetes mellitus.Population-based study in Rochester, Minnesota. Diabetes.1988;37: 405-412.
18. Haffner S M. Morales P A. Gruber M K. Hasuda H P. Stern M P. Cardiovascular risk factors in non-insulin-dependent diabetics with microalbuminuria . Arterioscler.Thromb 1995;13: 205-210.
19.Gollins V R. Dowse G K. Finch C F. Zimmet P Z. Linnane A W. Prevalence and risk factors for micro- and macroalbuminuria in diabetic subjects and entire population of Nauru, Diabetes.1989;38: 1602-1610.
20. Kunzelman G L. Knowler W C. Pettitt D J. Bennett P H.Incidence of proteinuria in type 2 diabetes mellitus in the Pima Indians. Kidney int.1989;35: 681-687.