Uranchimeg D. . Oyunbat B. ,  Amgalan Jr. Amarsaikhan B.¹

School of Dentistry, Health Sciences University of Mongolia

Mongolian Academy of Sciences

Sialolithiasis is one of the most common diseases of the salivary gland. The exact cause of the sialolith formation is unknown. Detailed knowledge of the pathogenesis of sialolithiasis and the composition of sialoliths are necessary to define new therapeutic procedures. The crystalline components of 30 sialoliths from human submandibular glands were investigated by X-ray powder diffraction analysis. All of the sialoliths localized in the ducts of the submandibular gland were composed of hydroxlapatite. However, with one exception, all of the sialoliths in the Warton's duct were composed of hydroxyapatite as well as whitlockite and brushite. Whitlockite was observed more often in the nucleus of the sialoliths and it was a common co- phase along with hydroxylapatite. The nucleus of one sialolith consisted of brushite and the cortex showed a co- phase of hydroxylapatite and brushite. X-ray diffraction analysis detected the component elements in the calculi to be Ca, P, S, and Na. The major constituents were Ca and P.