Дорно дахины уламжлалт анагаах ухаан, 2012, 2(3)
EFFECT OF CALCITE ON OSTEOPOROSIS MODEL OF RATS INDUCED BY RETINOIC ACID
( Тойм өгүүлэл )
Өгүүллийн PDF-ийг татах
Абстракт
Objective: In this study, the effect of water solution of calcite on changes of behavior,
body and organ weight, and bone thickness in rat model of osteoporosis induced by
retinoic acid was examined.
Methods: Retinoic acid was administered to rats at concentrations of 70 mg/kg for 14
days. Induction of osteoporosis was evaluated by histological analysis. Once
osteoporosis had developed, calcite and Calci D-D were given to rats with foods for 30
days.
Results: After induction of osteoporosis, mucosal membranes of rats got erosive, fur
was curled up and lusterless, paws and nails were broken down. Animal get pretty tired
with poor appetite. No significant differences were observed in weights of internal
organs between the groups.
Нийтлэлийн нээгдсэн тоо: 250
