The National Center for Anthropology 1, The National Center for Anthropology 2Health Sciences University of Mongolia 3.
Өгүүллийн PDF-ийг татах
Studying relationship between morbidity and heterozygosity in genetic polymorphic loci of Mongolian population belongs among the most important problems. The problem has not yet been studied sufficiently well. Population based, and descriptive study designs were applied in this research work. We have firstly determined average frequency of heterozygote genotypes within 11 genetic polymorphic systems: ABO blood groups, esterase-D (EsD), glyoxalase-1 (GlO1), phosphoglucomutase-1 (PGM1), haptoglobin (Hp), group specific component (Gc), transferrin (Tf), third component of complement (C’3), and HLA-A, HLA-B, HLA-C loci of the Human Leukocyte Antigenic system. Average total morbidity of Mongolian population has been described based on international 10th classification of diseases. Relationship between average heterozygosity and average total morbidity of Mongolian population has been discovered by the geographical method. Statistically significant correlations appeared in the corridors of longitudes: 950-960, 980-990, 1030-1040, 1100-1110, 1160-1170, and in the corridors of latitudes: 420-430, 460-470, 470-480, 490-500, 500-510 between geographical distributions of average heterozygote’s frequency and average total morbidity.
