Nasengsang H,  Tomorbaatar N, Dungerdorj D 

Carry out a research to confirm the traditional processing technology of Mongolian medicine, Radix Aconiti Kusnezofii, which was recorded in Mongolian medicine Materia Medica. In order to standardize the processing of this Mongolian medicine, we have chosen the safest and the most effective way of processing technology by comparing and elucidating its effectiveness and security through scientific experiments. The variation of total alkaloids and ester-alkaloid contents were used as the criterion for comparing the quality of different traditional processed products; the experiment was established by the orthogonal experimental design for the selection of optimum factors. The result of our investigation notes that during all other processing methods, the content of Ester-alkaloid had stepped down in different degrees except Fructus Chebulae method. We selected traditional fumigation and steaming method, which was analyzed by the “Simple Testing Technique with Multiple Indicators”. The results of this research showed that the optimum conditions for preparing samples included the following steps: slicing the moistened material into piece of 2  - 4 mm thickness; and drying at 110o C for 2-4 hr. We observed that the most important factor on reducing the content of Ester-alkaloid is temperature (P <0.05). On the basis of our research it can be concluded that the method, where the moistened medical material is sliced has better-effect, a shorter cycle, without any adjuvant, convenient and suitable for industrialized mass production. The results of this experiment can be applied for the processing technology specification of Mongolian medicine, Radix Aconiti Kusnezofii.