Монголын Анагаахын Сэтгүүлүүдийн Холбоо (МАСХ)
Инноваци - Шинэ Санаа, Шинэ Нээлт, 2015, 16(9-1)
DIAGNOSTIC TREATMENT SITUATION OF BIPOLAR DISORDER
( Илтгэлийн хураангуй )
Gantsetseg1 T.,  Khishigsuren1 Z.,  OdongerelS.,  MinjmaaR.,  NyamtsetsegJ.,  SarantsetsegT.,  SugarmaaSh.,  GantulgaJ.,  TuyaN.
1- Mongolian National University of Medical Sciences  
2- Mongolian National Center for Mental Health
 
Background
WHO informed that across world an average of 565 young people aged 10 to 29 die every day through interpersonal violence. Some studies mentioned that anxiety was most frequently occurred as one of the psychological consequences among victims of child abuse. Recent research on effects of adverse early life experiences on central nervous system as stress systems (hypothalamus-pituitary-adrenal axisHPA) has provided a greater understanding of the link between childhood abuse and susceptibility to anxiety disorder. Therefore, this research was done to study anxiety among abused adolescents, some physical parameters and level of cortisol in saliva.
Methods
Total number of participants were 149 children aged between 11-16 years (number cases were 53, matched control subjects were 96). The Spence Children’s Anxiety Scale (SCAS; Spence, 1997) is a 38-item self-report questionnaire that assesses multiple symptoms of childhood anxiety disorders based on current diagnostic criteria. All participants were measured the cortisol in the saliva by Cortisol ELISA kit, Sigma, USA.
Results
Average age of all subjects in the study was 13.52±1.57 and 102 of all subjects were female and 47 were male. All anxiety symptoms of case group was statistically significance higher (p<0.01) than control group. The average amount of salivary cortisol of case group was (21.3±8.1 ng/ml) statistically significantly lower (p<0.01) than average amount of control group (31.56±16.9 ng/ml).
Conclusion
Anxiety was more frequently occurred among abused children and blunted cortisol responses might indicate a level of impaired HPA functioning that could constitute a vulnerability to psychopathology with exposure to anxiety.
 


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