Sarantuya E¹., Sainbileg S²., Uurtuya Sh¹

1- School of Biomedicine and Pharmacy, MNUMS

2- School of Medicine, MNUMS

BACKGROUND

Type 2 diabetes is known to be associated with elevated cardiovascular mortality and central pathological mechanism in is the process of atherosclerosis, which leads to narrowing of arterial walls throughout the body. Cardio-Ankle Vascular Index (CAVI) was developed as an index of arterial stiffness independently of early atherosclerosis.

OBJECTIVE

The aim of the study is to evaluate the correlation of arterial stiffness and atherosclerotic risk factors patients with Type 2 DM. 

METHOD

We used hospital-based onetime cross-sectional study for 52 type 2 DM patients aged 27-55 (mean age 46.7 ± 7.2) who were involved. Materials are collected by questionnaire, physical examination, blood analyzes and arterial stiffness is measured by VaSera VS-1000 device. 

RESULT 

Our result showed that CAVI was statistically significant on age (r=0.65 p=0.001), duration of disease (r=0.32 p=0.021), , systolic pressure (r = 0.54 p = 0.001), diastolic pressure (r = 0.54 p= 0.001), red blood cell (r=0.31, p=0.02) , hematocrit (r=0.32, p=0.02) respectively. CAVI, Body mass index and visceral fat were significantly higher in patients with hypertension than patients with normotensive.

CONCLUSION

This result suggests that age, hypertension and hematocrits improve arterial stiffness in type 2 diabetic patients. So it’s necessary to reduce the obesity and control the hypertension in type 2 diabetic patients to prevent from cardiovascular disease. 

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